Premature ovarian insufficiency: an International Menopause Society White Paper

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The British Menopause Society and Women's Health Concern recommendations on the management of women with premature ovarian insufficiency.

This guidance document by the British Menopause Society provides recommendations on the assessment and management of women with premature ovarian insufficiency (POI). The consequences of POI are related to the decline in ovarian function and estrogen deficiency associated with the condition. These can be short-term menopausal symptoms and long-term effects on bone and cardiovascular health, cog...

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Role of microRNAs in premature ovarian insufficiency

Premature ovarian insufficiency (POI) is a typical disorder of amenorrhea lasting for a minimum of 4 months. The typical characteristics comprised of declined estrogen and raised serum concentrations of follicle-stimulating hormone (FSH) in women <40-year-old, primarily originating from iatrogenic factors, karyotypic abnormalities, and genetic factors. However, the etiology of POI remains unkno...

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Adolescent Premature Ovarian Insufficiency Following Human Papillomavirus Vaccination

Three young women who developed premature ovarian insufficiency following quadrivalent human papillomavirus (HPV) vaccination presented to a general practitioner in rural New South Wales, Australia. The unrelated girls were aged 16, 16, and 18 years at diagnosis. Each had received HPV vaccinations prior to the onset of ovarian decline. Vaccinations had been administered in different regions of ...

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Possible Role of Autoimmunity in Patients with Premature Ovarian Insufficiency

BACKGROUND To evaluate the involvement of immune abnormality in patients with idiopathic premature ovarian insufficiency (POI). In addition to the known etiology, autoimmune disorders may be a pathologic mechanism for POI. MATERIALS AND METHODS Our study was a prospective controlled trial. Twenty women with POI, reasons other than autoimmune excluded, were enrolled in this study. The control ...

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ESHRE Guideline: management of women with premature ovarian insufficiency.

STUDY QUESTION What is the optimal management of women with premature ovarian insufficiency (POI) based on the best available evidence in the literature? SUMMARY ANSWER The guideline development group (GDG) formulated 99 recommendations answering 31 key questions on the diagnosis and treatment of women with POI. WHAT IS KNOWN ALREADY NA. STUDY DESIGN, SIZE, DURATION This guideline was pro...

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ژورنال

عنوان ژورنال: Climacteric

سال: 2020

ISSN: 1369-7137,1473-0804

DOI: 10.1080/13697137.2020.1804547